Epigenetic aging of the demographically non-aging naked mole-rat

oleh: Csaba Kerepesi, Margarita V. Meer, Julia Ablaeva, Vince G. Amoroso, Sang-Goo Lee, Bohan Zhang, Maxim V. Gerashchenko, Alexandre Trapp, Sun Hee Yim, Ake T. Lu, Morgan E. Levine, Andrei Seluanov, Steve Horvath, Thomas J. Park, Vera Gorbunova, Vadim N. Gladyshev

Format: Article
Diterbitkan: Nature Portfolio 2022-01-01

Deskripsi

The exceptionally long-lived naked mole-rat is characterized by the lack of increased mortality with aging. Here the authors perform epigenetic studies to show that naked mole-rats epigenetically age despite their non-increasing mortality rate.