Ultra-sensitive and rapid detection of nucleic acids and microorganisms in body fluids using single-molecule tethering
oleh: Wen-Chih Cheng, Troy Horn, Maya Zayats, Georges Rizk, Samuel Major, Hongying Zhu, Joseph Russell, Zhiguang Xu, Richard E. Rothman, Alfredo Celedon
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-09-01 |
Deskripsi
Culture-based diagnostic methods for microorganism detection are time-consuming but still the gold standard for conditions such as sepsis. Here the authors present an amplification and purification-free method to detect microorganisms in bodily fluids with high sensitivity: Single MOLecule Tethering (SMOLT).