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Abstract Observation of lepton number violation would represent a groundbreaking discovery with profound consequences for fundamental physics and as such, it has motivated an extensive experimental program searching for neutrinoless double beta decay. However, the violation of lepton number can be also tested by a variety of other observables. We focus on the possibilities of probing this fundamental symmetry within the framework of the Standard Model Effective Field Theory (SMEFT) beyond the minimal dimension-5. Specifically, we study the bounds on ∆L = 2 dimension-7 effective operators beyond the electron flavor imposed by all relevant low-energy observables and confront them with derived high-energy collider limits. We also discuss how the synergy of the analyzed multi-frontier observables can play a crucial role in distinguishing among different dimension-7 SMEFT operators.