3α,4α-Epoxy-5α-androstan-17β-yl acetate
oleh: L. C.R. Andrade, J. A. Paixão, M.J.M. de Almeida, F. M. Fernandes Roleira, E. J. Tavares da Silva
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2009-04-01 |
Deskripsi
The title compound, C21H32O3, results from modifications of the A and D rings of the aromatase substrate androstenedione. Ring A adopts a conformation between 10β-sofa and 1α,10β half-chair. Rings B and C are in slightly flattened chair conformations. Ring D approaches a 13β-envelope conformation, probably due to the acetoxy substituent, and shows a very short Csp3—Csp3 bond next to the epoxide ring, which is characteristic of 3–4 epoxides. .