Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells

oleh: Qi Chen, Hui Zhang, Yang Liu, Susanne Adams, Hanna Eilken, Martin Stehling, Monica Corada, Elisabetta Dejana, Bin Zhou, Ralf H. Adams

Format: Article
Diterbitkan: Nature Portfolio 2016-08-01

Deskripsi

Pericytes and vascular smooth muscle cells are crucial for functional blood vessels, but the developmental sources of these cells are incompletely understood. Here, the authors show that endocardial endothelial cells give rise to cardiac mural cells, which are controlled by Wnt signalling.