Sin Nombre Virus (SNV) Ig Isotype Antibody Response during Acute and Convalescent Phases of Hantavirus Pulmonary Syndrome
oleh: Pavel Bostik, Jorn Winter, Thomas G. Ksiazek, Pierre E. Rollin, Francois Villinger, Sherif R. Zaki, C.J. Peters, Aftab A. Ansari
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2000-04-01 |
Deskripsi
Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).