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HiFi metagenomic sequencing enables assembly of accurate and complete genomes from human gut microbiota
oleh: Chan Yeong Kim, Junyeong Ma, Insuk Lee
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
Here, the authors construct 102 complete metagenome-assembled genomes (cMAGs) from Pacific Biosciences (PacBio) high-accuracy long-read (HiFi) metagenomic sequencing, showing as high nucleotide accuracy as reference genomes and revealing that regions hard to assemble by short-read sequencing comprise mostly of genomic islands and rRNAs.