The ictal wavefront is the spatiotemporal source of discharges during spontaneous human seizures
oleh: Elliot H. Smith, Jyun-you Liou, Tyler S. Davis, Edward M. Merricks, Spencer S. Kellis, Shennan A. Weiss, Bradley Greger, Paul A. House, Guy M. McKhann II, Robert R. Goodman, Ronald G. Emerson, Lisa M. Bateman, Andrew J. Trevelyan, Catherine A. Schevon
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-03-01 |
Deskripsi
Epileptic brains display inhibitory restraint as manifested by the spread of synchronized activities being delayed in timing. Here, Elliot Smith and colleagues show fast-moving traveling wave that originates from the edge of ictal wavefront with subsequent depolarization and multiunit firing in the seizing brain regions in epileptic patients.