Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease

oleh: Tiago C. Silva, Juan I. Young, Lanyu Zhang, Lissette Gomez, Michael A. Schmidt, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

DNA methylation differences in Alzheimer’s disease have been previously reported, although the interpretation of the differences is unclear. Here, the authors performed epigenome-wide meta-analyses of DNA methylation in blood and brain, and developed a methylation-based risk prediction model for AD.