Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis
oleh: Morteza Abyadeh, Fatemeh Heydarinejad, Maliheh Khakpash, Yaser Asefi, Sakineh Shab-Bidar
Format: | Article |
---|---|
Diterbitkan: | Taylor & Francis Group 2020-04-01 |
Deskripsi
Objective The aim of this meta-analysis was to examine the association of ApoE polymorphism with the risk of developing PE. Methods A comprehensive search was carried out through PubMed, Scopus, and Embase. The ORs with corresponding 95% CIs were extracted. Fixed model was used for meta-analysis and in case of existing heterogeneity a random-effects model was applied. Results Association of ApoE polymorphism with the risk of developing PE was not statistically significant (OR = 0.86, 95% CI: 0.67–1.11; OR = 0.92, 95%CI: 0.73–1.15, respectively for ε2 and ε4). Conclusion ApoE polymorphism might not be associated with the risk of PE.