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The present study was conducted to epidemiological, serological and clinical of Infectious Bursal Disease (IBD) ¶on Algerian broiler chicken (45 flocks/1350 sera) using indirect Enzyme-Linked Immuno-Sorbent Assay (ELISA) method and to assess the influence of some risk factors related to this disease. Among all investigated flocks, IBD was the most seroprevalent disease (73.33%). The results show the effect of risk factors, the antibody titers were elevated in the herd recorded a high mortality (more than 10%) compared with those recorded a low mortality (less than 10%) (p = 0.009). However, more than flocks 30 days old flocks were less seropositive those less aged of 30 days (p = 0.002). Therefore, the antibody titers were elevated in herds with bad hygiene compared with good hygiene (p = 0.04) At last, when broiler chicken were not boosted by IBD vaccine, flocks appeared to be more seropositivity (p = 0.03). This study determined that IBD is a dominant viral disease in broilers. Many factors are responsible for the development of this disease.