Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines
oleh: C. Granier, C. Blanc, S. Karaki, T. Tran, H. Roussel, E. Tartour
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2017-11-01 |
Deskripsi
Resident memory CD8+T cells (TRM) usually defined by the CD103 marker represent a new subset of long-lived memory T cells that remain in the tissues. We directly demonstrate their specific role in cancer vaccine-induced tumor regression. In human, they also seem to play a major role in tumor immunosurveillance.