Comparative survey of the relative impact of mRNA features on local ribosome profiling read density
oleh: Patrick B. F. O’Connor, Dmitry E. Andreev, Pavel V. Baranov
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-10-01 |
Deskripsi
Ribosome profiling data can suffer from uneven coverage which hampers estimation of elongation rates. Connor et al.present an enhanced data smoothing method for Ribo-seq data and highlight significant variability in sequence determinants of ribosome density in publicly available data sets.