Lung parenchymal calcifications in a child with cystic fibrosis
oleh: Heidi Lynch, Frank Qian, Matthew D. Wong, Rahul J. Thomas, Nitin Kapur
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2022-05-01 |
Deskripsi
Abstract We describe a 6‐year‐old girl with homozygous p.Phe508del cystic fibrosis with severe multi‐lobar bronchiectasis and obstructive lung disease who was found to have prominent parenchymal calcifications in the right middle lobe on a computed tomography scan of the chest. Histopathology from the calcified area of lung biopsy showed fibrous tissue with chronic inflammation with CD3+ T‐lymphocytes and macrophages with no granulomas. Dystrophic calcification was seen within this necrotic debris.