Wnt4 and ephrinB2 instruct apical constriction via Dishevelled and non-canonical signaling
oleh: Jaeho Yoon, Jian Sun, Moonsup Lee, Yoo-Seok Hwang, Ira O. Daar
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Apical constriction is known to be critical for neural tube closure, but the signals that induce this process have not been fully characterized. Here Yoon et al. identify a signaling complex that instructs actomyosin contractions during apical constriction and show that it is required for neural tube closure.