Effectiveness of therapeutic plasma exchange in case of rare neurological disorder Isaacs syndrome

oleh: Parmatma Prasad Tripathi, Sangeeta Kumari, Nandita Prabhat, Divjot Singh Lamba, Rekha Hans, Manoj Kumar Goyal, Vivek Lal, Ratti Ram Sharma

Format: Article
Diterbitkan: Wolters Kluwer Medknow Publications 2023-01-01

Deskripsi

Isaacs syndrome is a disease characterized by nerve hyperexcitability and pseudomyotonia and treated with immunomodulatory and symptomatic therapy approaches. Here, we report a case of anti-(leucine-rich glioma-inactivated 1) antibody-positive patient diagnosed as Isaacs syndrome and accomplished a nearly complete response to only four sessions of therapeutic plasma exchange (TPE). Our experience suggests that TPE along with other immunomodulatory agents may be beneficial and well-tolerated approach in patient with Isaacs syndrome.