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ABSTRACT A case of multiple liver abscesses in a patient with situs inversus totalis is presented. Initially the patient was treated conservatively and remained symptom free for 4 days of hospital stay. On a follow up visit after 1 week the patient had high grade spiking fever and ultrasonography showed expanding multiple abscesses. The patient was restarted on intravenous antibiotics which resolved the disease. Keywords:   This article may be cited as:     Situs Inversus Viscerum, Situs Inversus Totalis, Liver Abscess, Kartagener’s Syndrome, Situs Solitus,DNAH11, Mirror Image Mufti TS, Khan M, Alam MB, Mufti SE . Situs inversus totalis with liver abscess. KUST Med J 2009; 1 (1): 21-23