Proteomics of protein trafficking by in vivo tissue-specific labeling
oleh: Ilia A. Droujinine, Amanda S. Meyer, Dan Wang, Namrata D. Udeshi, Yanhui Hu, David Rocco, Jill A. McMahon, Rui Yang, JinJin Guo, Luye Mu, Dominique K. Carey, Tanya Svinkina, Rebecca Zeng, Tess Branon, Areya Tabatabai, Justin A. Bosch, John M. Asara, Alice Y. Ting, Steven A. Carr, Andrew P. McMahon, Norbert Perrimon
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-04-01 |
Deskripsi
The network of proteins secreted for interorgan communication is poorly understood. Here, the authors develop a method, based on protein labeling, to study cell-specific secretomes and interorgan protein trafficking, and demonstrate their approach in Drosophila and mouse models.