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Transepithelial photorefractive keratectomy (TransPRK) is an established surface ablation technique used to correct refractive errors. Using anterior segment optical coherence (AS-OCT), it is now possible to measure the epithelium thickness and input these data into the laser platform. In this study, we explore whether better results were obtained in this way. To this end, we retrospectively analyze the results from a low-myopia group treated with a customized epithelium thickness, as measured using AS-OCT, and compare them with the results from a group treated with an optimized standard epithelium thickness. The customized epithelium profile group contains more eyes with vision better than 20/20, and more eyes in this group gain one line of corrected distance visual acuity (CDVA). In conclusion, with the customized epithelium thickness, we obtain superior results using TransPRK in low-myopia corrections.