Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

oleh: Yang-Hee Kim, Xia Yang, Liyang Shi, Stuart A. Lanham, Jons Hilborn, Richard O. C. Oreffo, Dmitri Ossipov, Jonathan I. Dawson

Format: Article
Diterbitkan: Nature Portfolio 2020-03-01

Deskripsi

Nanoclays have been used in composites and for drug delivery but have suffered from a trade-off in properties when used for both. Here the authors report on the use of bisphosphonate interactions with nanoclay edges to made drug loaded composites without compromising materials properties or drug loading.