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It has been suggested that in doubtful cases of coeliac disease, a high CD3⁺ T-cell receptor gamma delta⁺ (TCR&#947;&#948;⁺) intraepithelial lymphocyte count increases the likelihood of coeliac disease. Aim: To evaluate the diagnostic accuracy of both an isolated increase of TCR&#947;&#948;⁺ cells and a coeliac lymphogram (increase of TCR&#947;&#948;⁺ <i>plus</i> decrease of CD3^&#8722; intraepithelial lymphocytes) evaluated by flow cytometry in the diagnosis of coeliac disease. Methods: The literature search was conducted in MEDLINE and EMBASE. The inclusion criteria were: an article that allows for the construction of a 2 &#215; 2 table of true and false positive and true and false negative values. A diagnostic accuracy test meta-analysis was performed. Results: The search provided 49 relevant citations, of which 6 were selected for the analysis, which represented 519 patients and 440 controls. Coeliac lymphogram: The pooled S and Sp were 93% and 98%, without heterogeneity. The area under the SROC curve (AUC) was 0.98 (95% CI, 0.97&#8722;0.99). TCR&#947;&#948;⁺: Pooled S and Sp were both 95%, with significant heterogeneity. The AUC was 0.97 (95% CI, 0.95&#8722;0.98). <b>Conclusions</b>: Both TCR&#947;&#948;⁺ count and coeliac lymphogram assessed by flow cytometry in duodenal mucosal samples are associated with a high level of diagnostic accuracy for and against coeliac disease.