Ruler elements in chromatin remodelers set nucleosome array spacing and phasing
oleh: Elisa Oberbeckmann, Vanessa Niebauer, Shinya Watanabe, Lucas Farnung, Manuela Moldt, Andrea Schmid, Patrick Cramer, Craig L. Peterson, Sebastian Eustermann, Karl-Peter Hopfner, Philipp Korber
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
Although chromatin remodelers have been shown to align nucleosome arrays to barriers and to generate spacing regularity among nucleosomes within arrays, it has remained unclear how the distance to barrier and the spacing length are determined in absolute terms. Here, the authors reveal that remodelers contain a ‘ruler’ element that sets remodeler-specific alignment and spacing distances when generating nucleosome arrays.