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In recent years, a growing desire has emerged to use Six Sigma techniques. Six Sigma can win companies to improve quality and reduce expenses in today's competitive world. But the important thing is that this tool should be used in organizations that are prepared; unprepartion for Six Sigma implementation leads to frustration among staff at different organizational levels and finally creates resistance and opposition against the project. The aim of this research is to assess the readiness of companies to provide Six Sigma implementation. For this purpose, first readiness indicators were identified for the implementation of Six Sigma, then to determine the relationship between these indicators interpretative structural modeling was applied. Finnaly through ANP weight of indictors were determined.The results showed that the "leadership and vision", "right choice" and "management improvement process" are more important.