The F-pilus biomechanical adaptability accelerates conjugative dissemination of antimicrobial resistance and biofilm formation

oleh: Jonasz B. Patkowski, Tobias Dahlberg, Himani Amin, Dharmender K. Gahlot, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Matthew S. Francis, Joseph L. Baker, Magnus Andersson, Tiago R. D. Costa

Format: Article
Diterbitkan: Nature Portfolio 2023-04-01

Deskripsi

Enteropathogenic bacteria use extracellular appendages, known as F-pili, to share plasmids carrying antibiotic resistance genes. Here, the authors show that F-pili are highly flexible but robust at the same time, and this is important for plasmid transfer and formation of biofilms that protect against the action of antibiotics.