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The F-pilus biomechanical adaptability accelerates conjugative dissemination of antimicrobial resistance and biofilm formation
oleh: Jonasz B. Patkowski, Tobias Dahlberg, Himani Amin, Dharmender K. Gahlot, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Matthew S. Francis, Joseph L. Baker, Magnus Andersson, Tiago R. D. Costa
Format: | Article |
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Diterbitkan: | Nature Portfolio 2023-04-01 |
Deskripsi
Enteropathogenic bacteria use extracellular appendages, known as F-pili, to share plasmids carrying antibiotic resistance genes. Here, the authors show that F-pili are highly flexible but robust at the same time, and this is important for plasmid transfer and formation of biofilms that protect against the action of antibiotics.