Building a Chinese pan-genome of 486 individuals
oleh: Qiuhui Li, Shilin Tian, Bin Yan, Chi Man Liu, Tak-Wah Lam, Ruiqiang Li, Ruibang Luo
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-08-01 |
Deskripsi
Qiuhui Li et al. report a pan-genome sequence study in Han Chinese genomes. They find 276 Mbp of DNA sequences (absent in the current human reference), and report that 46.646 Mbp common sequences improved the accuracy of variant calling and mapping rate when added to the reference genome.