PRELIMINARY STRUCTURE–ACTIVITY RELATIONSHIP STUDY OF HEPTAMETHINE INDOCYANINE DYES FOR TUMOR-TARGETED IMAGING
oleh: QINYUAN GUO, SHENGLIN LUO, QINGRONG QI, CHUNMENG SHI
| Format: | Article |
|---|---|
| Diterbitkan: | World Scientific Publishing 2013-01-01 |
Deskripsi
Our research has identified a couple of near-infrared (NIR) heptamethine indocyanine dyes exhibiting preferential tumor accumulation property for in vivo imaging. On the basis of our foregoing work, we describe here a preliminary structure–activity relationship (SAR) study of 11 related heptamethine indocyanine dyes and several essential requirements of these structures for in vivo tumor-targeted imaging.