A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors

oleh: Zhengwen An, Maja Sabalic, Ryan F. Bloomquist, Teresa E. Fowler, Todd Streelman, Paul T Sharpe

Format: Article
Diterbitkan: Nature Portfolio 2018-01-01

Deskripsi

Mouse incisors constantly renew from a slow cycling population of mesenchymal stem cells. Here, the authors show that upon cutting of adult incisors, a sub-population of dental mesenchymal stem cells reactivates, allowing an increased growth rate and rapid regeneration.