Targeting the AXL signaling pathway in ovarian cancer
oleh: Ruby Yun-Ju Huang, Jane Antony, Tuan Zea Tan, David Shao-Peng Tan
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2017-03-01 |
Deskripsi
In a recent publication in Science Signaling, we showed that a Mes molecular subtype of epithelial ovarian cancer (EOC) harboring epithelial-mesenchymal transition (EMT) features has a unique signaling network downstream of the GAS6/AXL pathway. Our finding leads to a potential strategy for treating the Mes subtype of EOC by targeting AXL.