The in vivo genetic program of murine primordial lung epithelial progenitors
oleh: Laertis Ikonomou, Michael J. Herriges, Sara L. Lewandowski, Robert Marsland, Carlos Villacorta-Martin, Ignacio S. Caballero, David B. Frank, Reeti M. Sanghrajka, Keri Dame, Maciej M. Kańduła, Julia Hicks-Berthet, Matthew L. Lawton, Constantina Christodoulou, Attila J. Fabian, Eric Kolaczyk, Xaralabos Varelas, Edward E. Morrisey, John M. Shannon, Pankaj Mehta, Darrell N. Kotton
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-01-01 |
Deskripsi
The identity of the earliest murine in vivo lung epithelial progenitors (marked by NKX2-1 expression) is unclear. Here, the authors use single-cell RNA sequencing to define the genetic program of these lung primordial progenitors, which will improve in vitro lung specification of pluripotent stem cells.