Research progress of HIF-1 mediated autophagy in cardiac diseases

oleh: ZHANG Liu-jie, LI Jing, WU Bo

Format: Article
Diterbitkan: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2021-08-01

Deskripsi

Hypoxia-inducible factor 1 (HIF-1) regulates the expression of target genes to keep the balance between oxygen supply and oxygen consumption, maintains oxygen homeostasis. HIF-1 regulates autophagy in the cardiovascular system, which involves the HIF target gene BNIP3.