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Research progress of HIF-1 mediated autophagy in cardiac diseases
oleh: ZHANG Liu-jie, LI Jing, WU Bo
Format: | Article |
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Diterbitkan: | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2021-08-01 |
Deskripsi
Hypoxia-inducible factor 1 (HIF-1) regulates the expression of target genes to keep the balance between oxygen supply and oxygen consumption, maintains oxygen homeostasis. HIF-1 regulates autophagy in the cardiovascular system, which involves the HIF target gene BNIP3.