Fine-tuning the efficiency of para-hydrogen-induced hyperpolarization by rational N-heterocyclic carbene design
oleh: Peter J. Rayner, Philip Norcott, Kate M. Appleby, Wissam Iali, Richard O. John, Sam J. Hart, Adrian C. Whitwood, Simon B. Duckett
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-10-01 |
Deskripsi
Hyperpolarization methods play a crucial role in the in vivo observation of molecular metabolism by MRI techniques. Here, the authors develop NHC-containing iridium complexes which improve the NMR detectability of 1H, 13C and 15N nuclei via transfer of latent magnetism of para-hydrogen into a substrate.