Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions

oleh: Timothy M. OʼShea, Alexander L. Wollenberg, Jae H. Kim, Yan Ao, Timothy J. Deming, Michael V. Sofroniew

Format: Article
Diterbitkan: Nature Portfolio 2020-12-01

Deskripsi

Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.