Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease
oleh: Troy L. Merry, Chris P. Hedges, Stewart W. Masson, Beate Laube, Doris Pöhlmann, Stephan Wueest, Michael E. Walsh, Myrtha Arnold, Wolfgang Langhans, Daniel Konrad, Kim Zarse, Michael Ristow
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-04-01 |
Deskripsi
Hyper-insulinemia associated with excess calorie intake may cause metabolic dysfunction. Here the authors report that mice with partially reduced insulin receptor expression in peripheral tissues are protected from and experience reversal of fatty liver disease.