Tumor fractions deciphered from circulating cell-free DNA methylation for cancer early diagnosis
oleh: Xiao Zhou, Zhen Cheng, Mingyu Dong, Qi Liu, Weiyang Yang, Min Liu, Junzhang Tian, Weibin Cheng
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-12-01 |
Deskripsi
‘Circulating cell-free DNA can be used to predict cancer, but it is more challenging to assess in early stage cancer. Here, the authors created a diagnostic model using tumor fractions deciphered from circulating cfDNA methylation signatures, which exhibited an 86% sensitivity in detecting early-stage cancer.