Relationship between mucosal TNF-α expression and Th1, Th17, Th22 and Treg responses in Helicobacter pylori infection
oleh: Ghorbanali Rahimian, Milad Shahini Shams Abadi, Yousef Mirzaei, Ali Hussein Mer, Reza Ahmadi, Fatemeh Azadegan-Dehkordi
| Format: | Article |
|---|---|
| Diterbitkan: | SpringerOpen 2022-09-01 |
Deskripsi
Key points Expression of TNF-α was significantly increased in the PUD group than the gastritis group. Notably, TNF-α expression had a significant positive correlation with the frequency of Th1/Th17/Th22 lymphocytes in the PUD group. These findings indicate the importance of increasing TNF-α with Th1, Th17, Th22 responses increase as an important risk factor for PUD in context of H. pylori infection.