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Diorganotin(IV) and triorganotin(IV) derivatives of the types R2SnA (R=n-Bu and n-octyl) and (R3Sn)2A (R=n-Bu), where A is the anion of albendazole {methyl[(5-propylsulfanyl-3H-benzoimidazol-2-yl) amino]formate}, ofloxacin {(RS)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13] trideca-5(13),6,8,11-tetraene-11-carboxylicacid} and 3-carboxypropyldisulfide, have been synthesized. The complexes 1–9 obtained were characterized by elemental analysis as well as infrared (Fourier transform infrared), nuclear magnetic resonance (1H, 13C and 119Sn NMR) and ultraviolet spectroscopy. On the basis of these spectroscopic studies it was proposed that diorganotin complexes of 3-carboxypropyldisulfide having 1:1 stoichiometry and complexes of albendazole and ofloxacin having 1:2 stoichiometry show tetrahedral geometry around the tin atom with monodentate behavior of the carboxylate group in ofloxacin and 3-carboxypropyldisulfide. Triorganotin complexes of 3-carboxypropyldisulfide having 1:1 stoichiometry and complexes of ofloxacin and albendazole having 1:2 stoichiometry show trigonal bipyramidal geometry. The ligand molecule is bound to the Sn atom through carboxyl oxygen atoms in ofloxacin and 3-carboxypropyldisulfide, and to the nitrogen atom in albendazole. The biological activity of the synthesized complexes 4, 5 and 6 has been screened against Candida albicans.