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1053 Preclinical pharmacodynamic characterization of STK-026: a novel IL-12 partial agonist for cancer with maintained CD8 T cell activity, reduced NK-mediated toxicity and an improved therapeutic window

oleh: Martin Oft, Michael Totagrande, Luis Zuniga, David B Rosen, Priyanka Balasubrahmanyam, Zhenya Koliesnik, Ryan Burgess, Kim Q Tran, Michele Bauer, Bharghavi Jayaraman, Cindy Buffone, Jan Emmerich, Deepti Chaturvedi, Deepti Rokkam, Rene De Waal Malefyt, Heiko Greb, Navneet Ratti, Sandro Vivona, Robert Kastelein, Patrick Lupardus