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Ependymomas outside the confines of the cranium and spinal cord are rare. The occurrence of these tumors in an extradural, sacrococcygeal, or subcutaneous location may prove challenging, particularly in the absence of any obvious central nervous system connection. The origin of these tumors from subcutaneous sacrococcygeal ependymal rests is postulated on the basis of earlier reports. We describe 1 such rare extradural case of myxopapillary ependymoma in a 30-year-old female, which presented as a non-healing ulcer in the left gluteal area. It was initially diagnosed and was being treated as an infected epidermoid cyst. Clinical and histopathological features are described, and a brief review of published reports is presented.