Endogenous antibody response to SARS-CoV-2 in patients who received monoclonal antibodies against COVID-19: A systematic review

oleh: Andrea Lombardi, Cecilia AzzarĂ , Giulia Renisi, Giulia Viero, Andrea Gori, Alessandra Bandera

Format: Article
Diterbitkan: Elsevier 2022-12-01

Deskripsi

Passive immunization with mAbs has been employed in COVID-19. We performed a systematic review of the literature assessing the endogenous humoral immune response against SARS-CoV-2 in patients treated with mAbs. Administration of mAbs in seronegative patients led to a reduction in both antibody titres and neutralizing activity against the virus.