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The easy and scalable synthesis, biocompatibility, one-dimensionality, high aspect ratio, viability for surface modifications, and the ability for cargo-loading and release make organic nanotubes ideal candidates for smart coatings with slow and controlled release corrosion inhibitors and anti-biofouling agents. The wide-ranging applicability of organic nanotubes as controlled release nanocarriers for smart anti-corrosion and anti-biofouling coatings is foreseen.