Research on the Medicinal Chemistry and Pharmacology of <i>Taxus</i> × <i>media</i>

oleh: Xinyu Gao, Ni Zhang, Weidong Xie

Format: Article
Diterbitkan: MDPI AG 2024-05-01

Deskripsi

<i>Taxus</i> × <i>media</i>, belonging to the genus <i>Taxus</i> of the Taxaceae family, is a unique hybrid plant derived from a natural crossbreeding between <i>Taxus cuspidata</i> and <i>Taxus baccata</i>. This distinctive hybrid variety inherits the superior traits of its parental species, exhibiting significant biological and medicinal values. This paper comprehensively analyzes <i>Taxus × media</i> from multiple dimensions, including its cultivation overview, chemical composition, and multifaceted applications in the medical field. In terms of chemical constituents, this study delves into the bioactive components abundant in <i>Taxus × media</i> and their pharmacological activities, highlighting the importance and value of these components, including paclitaxel, as the lead compounds in traditional medicine and modern drug development. Regarding its medicinal value, the article primarily discusses the potential applications of <i>Taxus × media</i> in combating tumors, antibacterial, anti-inflammatory, and antioxidant activities, and treating diabetes. By synthesizing clinical research and experimental data, the paper elucidates the potential and mechanisms of its primary active components in preventing and treating these diseases. In conclusion, <i>Taxus × media</i> demonstrates its unique value in biological research and tremendous potential in drug development.