Cutaneous Metastases from Nasopharyngeal Carcinoma: A Rare Manifestation

oleh: Halimuddin Sawali, Mohd Razif Mohamad Yunus, Ong Cheng Ai, Primuharsa Putra Sabir Husin Athar

Format: Article
Diterbitkan: Philippine Society of Otolaryngology-Head and Neck Surgery, Inc. 2010-12-01

Deskripsi

Objective: In this article, we report on two unusual cases of advanced nasopharyngeal carcinoma (NPC) with distant cutaneous metastases.   Methods:                  Design: Case Report                  Setting: Tertiary Referral Center                  Patients: Two Results:  Two patients with advanced NPC developed multiple nodular skin metastases, one after completing radiotherapy and another during concurrent chemo-radiotherapy. Biopsies of these skin lesions confirmed metastatic NPC and both patients succumbed to the disease.   Conclusion: Nasopharyngeal carcinoma with skin metastases carries a very poor prognosis. Early detection, diagnosis and treatment are still the best management strategy for nasopharyngeal carcinoma.   Keywords:  Nasopharynx, nasopharyngeal carcinoma, skin metastases, cutaneous                           metastases