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A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry
oleh: Samuel Wein, Byron Andrews, Timo Sachsenberg, Helena Santos-Rosa, Oliver Kohlbacher, Tony Kouzarides, Benjamin A. Garcia, Hendrik Weisser
Format: | Article |
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Diterbitkan: | Nature Portfolio 2020-02-01 |
Deskripsi
Mass spectrometry (MS) enables identification of modified RNA residues, but high-throughput processing is currently a bottleneck. Here, the authors present a free and open-source database search engine for RNA MS data to facilitate reliable identification of modified RNA sequences.