Design, Synthesis and Anti-HIV Integrase Evaluation of 4-Oxo-4H-quinolizine-3-carboxylic Acid Derivatives
oleh: Li-Ming Hu, Ru-gang Zhong, Zi-Guo Jiao, Cheng-Chu Zeng, Yi-Sheng Xu
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2009-02-01 |
Deskripsi
4-Oxo-4H-quinolizine-3-carboxylic acid derivatives bearing sulfamido, carboxylamido, benzimidazole and benzothiazole substituents have been designed and synthesized. The structures of these new compounds were confirmed by 1H-NMR, 13C- NMR, IR and ESI (or HRMS) spectra. Compounds were screened for possible HIV integrase inhibitory activity.