Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex
oleh: Yoel A. Klug, Justin C. Deme, Robin A. Corey, Mike F. Renne, Phillip J. Stansfeld, Susan M. Lea, Pedro Carvalho
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-10-01 |
Deskripsi
Lipid droplet biogenesis is orchestrated by the conserved membrane protein Seipin via an unknown mechanism. Here, the authors use structural, biochemical and molecular dynamics simulation approaches to reveal the mechanism of lipid droplet formation by the yeast Seipin Sei1 and its partner Ldb16.