Organocatalytic synthesis of chiral tetrasubstituted allenes from racemic propargylic alcohols
oleh: Deyun Qian, LinLin Wu, Zhenyang Lin, Jianwei Sun
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-09-01 |
Deskripsi
Axially chiral allenes that are normally present in natural products, bioactive molecules, organocatalysts, and functional materials are usually produced from propargylic derivatives. Here, the authors show direct use of propargylic alcohols for catalytic asymmetric allene synthesis.