A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer.
oleh: Christopher G Hubert, Shaun R Stauffer, Justin D Lathia
| Format: | Article |
|---|---|
| Diterbitkan: | Public Library of Science (PLoS) 2023-09-01 |
Deskripsi
Cancer stem cells drive tumor growth and survival via self-renewal and therapeutic resistance, but the upstream mechanisms are not well defined. In this issue of PLOS Biology, a study in colon cancer reveals a new signalling network that links epigenetic regulation to these phenotypes.