Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure
oleh: Nicholas P. Stone, Gabriel Demo, Emily Agnello, Brian A. Kelch
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-10-01 |
Deskripsi
Viral capsids need to protect the genome against harsh environmental conditions and cope with high internal pressure from the packaged genome. Here, the authors determine the structure of the thermostable phage P74-26 capsid at 2.8-Å resolution and identify features underlying enhanced capsid capacity and structural stability.