Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection

oleh: Julian A. Rycroft, Bridget Gollan, Grzegorz J. Grabe, Alexander Hall, Angela M. Cheverton, Gerald Larrouy-Maumus, Stephen A. Hare, Sophie Helaine

Format: Article
Diterbitkan: Nature Portfolio 2018-05-01

Deskripsi

The recalcitrance of many infections to antibiotic treatment may be due to the presence of ‘persisters’, or non-growing, antibiotic-tolerant bacteria. Here, the authors study the structures and functions of aminoacyl-tRNA acetyltransferase toxins, and their roles in persister formation in Salmonella.