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The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni
oleh: Gaurav Dugar, Sarah L. Svensson, Thorsten Bischler, Sina Wäldchen, Richard Reinhardt, Markus Sauer, Cynthia M. Sharma
Format: | Article |
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Diterbitkan: | Nature Portfolio 2016-05-01 |
Deskripsi
The CsrA protein binds to and represses translation of certain bacterial mRNAs. Here, Dugar et al. show for the human pathogen Campylobacter jejunithat the major flagellin mRNA acts as both a target and a regulatory 'sponge' for CsrA, and is localized at the cell poles in a translation-dependent manner.